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Protein Science (2004), 13:1948-1949. Published by Cold Spring Harbor Laboratory Press. Copyright © 2004 The Protein Society
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FOR THE RECORD

The progress of membrane protein structure determination

Stephen H. White

Department of Physiology and Biophysics and Program in Macromolecular Structure, University of California at Irvine, Irvine, California 92697, USA

(RECEIVED February 29, 2004; FINAL REVISION February 29, 2004; ACCEPTED April 20, 2004)



Abstract

The rate of membrane protein (MP) structure determination has been examined for the 18-year period following the publication of the first high-resolution crystal structure. The growth is solidly exponential, but lags behind the rate for soluble proteins during the equivalent time period.

Keywords: protein databases; crystallography; database growth; soluble proteins


Reprint requests to: Stephen H. White, Department of Physiology and Biophysics, Medical Sciences I, D-346, University of California at Irvine, Irvine, CA 92697-4560, USA; e-mail: blanco{at}helium.biomol.uci.edu; fax: (949) 824-8540.

Article and publication are at http://www.proteinscience.org/cgi/doi/10.1110/ps.04712004.


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