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Protein Science, Vol 6, Issue 4 808-815, Copyright © 1997 by Cold Spring Harbor Laboratory Press
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E. WALLIN, T. TSUKIHARA, S. YOSHIKAWA, G. V. HEIJNE and A. ELOFSSON
Department of Biochemistry, Stockholm University, S-106 91 Stockholm, Sweden
We have analyzed the structure of mitochondrial cytochrome c oxidase in terms of general characteristics thought to be important for describing the architecture of helix bundle membrane proteins. Many aspects of the structure are similar to what has previously been found for the photosynthetic reaction center and bacteriorhodopsin. Our results lead to a considerably more precise general picture of membrane protein architecture than has hitherto been possible to obtain.
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