Integrin IIb3:ligand interactions are linked to binding-site remodeling

Supplemental Research Data

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• PDF File (528 KB) - Supplementary Figure 1. Analytical characterization of echistatin mutants by reversed-phase HPLC. (a) R24K; (b) D26E; (c) rEch(1-49)M28L; (d) D26A; (e) D27F; (f) D27W
  Supplemenatry Figure 2. 1H NMR spectra of wild-type and mutant echistatins. Amide/aromatic region for (a) rEch(1-49)M28L; (b) R24A; (c) R24K; (d) D26A; (e) D26E; (f) D27W; (g) D27F; (h) wild-type, reduced/alkylated