All three Ca2+-binding loops of photoproteins bind calcium ions: The crystal structures of calcium-loaded apo-aequorin and apo-obelin
Protein Sci Deng et al.
14: 663
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Table S1 collects the calcium-ligand distances for the two Ca2+-loaded
apo-photoproteins.
Figure S1 compares the sequences of the aequorin studied by Head et al., 2000, the aequorin-A7 used in this work, obelin, and the Ca-loaded forms.
Figure S2 shows the loop I to loop II interactions of EF-hand motifs AB and CD.
Figure S3 shows the loop III to loop IV interactions of EF-hand motifs EF and GH.
Figure S4 shows the repositioning of the EF-hand motifs of obelin on calcium binding.