Supplemental Research Data

Files in this Data Supplement:

• PDF File 102 KB) - Sequence alignment of the N-terminus of human TRPV1 through V6. Ankyrin repeats are labeled ANK1-6 as seen in the crystal structure of TRPV2. The TRPV2 residues in each helical pair of the repeats are underlined with residues involved in the hydrophobic patch shaded grey. TRPV residues identical to the consensus ankyrin repeat sequence (as in Fig. 1B) are shown in bold. Clustal W was used to generate the sequence alignment.