Structure of the Q67H mutant of R67 dihydrofolate reductase-NADP+ complex reveals a novel cofactor binding mode
Protein Sci Divya et al.
16: 1063
Supplemental Research Data
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The supplemental material contains a figure showing a stereo view of a ternary model and a table of distances derived from X-ray/model/ILOE studies. Details related to comparison of NADP+ and folate binding environment, molecular basis for cooperativity between cofactor and folate binding, and construction of a catalytic ternary model are presented.
