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Cover Illustration: Ribbon diagram of E. coli transcription regulator in complex with its DNA substrate (Parkinson et al. 1996 [Nat. Struct. Biol. 3: 837]), illustrating areas of protein flexibility. Regions predicted to be flexible by Deuterium eXchange Mass Spectroscopy (DXMS) are colored green while expected disordered stretches calculated computationally with SEG are colored red. (See Spraggon et al., pp. 3187–3199.).
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