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Cover Illustration: Interactions between Appr-1″-pase and its catalytic product ADP-ribose in the product-bound state. Bonds of protein residues are shown in cyan; ADP-ribose and ethylene glycol are shown in gray. Carbon, Oxygen, Nitrogen, and phosphorus atoms are shown in green, red, blue, and purple, respectively. The purple dashed lines indicate the hydrogen bonding. (See Kumaran et al., pp. 719-726)

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