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Cover Illustration: Acetohydroxyacid synthase isozyme III (AHAS) is an essential enzyme for valine biosynthesis in bacteria, and is composed of a tetrameric assembly of two catalytic and two small regulatory subunits. The structure of a dimer of the AHAS small regulatory subunit from Nitrosomonas europea is shown. The zoomed area shows a detailed view of the loop involved in Ca²⁺ binding. (see Petkowski et al., pp. 1360-1367.)